An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.
ENTRAF ID | ENTRAF0012 |
Gene name | ethR |
Uniprot ID | ETHR_MYCTU |
Organism | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
Aminoacid sequence | MTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR |
FASTA file | Download |
Length | 216 |
Function Uniprot | Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH). |
Role | Repressor |
Protein family | TetR/AcrR |
Structure (PDB ID) | 1T56 |