ENTRAF

An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.

Transcription factor information

General information

ENTRAF ID ENTRAF0024
Gene name perR
Uniprot ID PERR_BACSU
Organism Bacillus subtilis (strain 168)
Aminoacid sequence MAAHELKEALETLKETGVRITPQRHAILEYLVNSMAHPTADDIYKALEGKFPNMSVATVYNNLRVFRESGLVKELTYGDASSRFDFVTSDHYHAICENCGKIVDFHYPGLDEVEQLAAHVTGFKVSHHRLEIYGVCQECSKKENH
FASTA file Download
Length 145

Functional information

Function Uniprot Hydrogen and organic peroxide sensor. Represses the expression of a regulon of peroxide-inducible genes such as katA, ahpC, ahpF, the heme biosynthesis operon (hemAXCDBL), fur, perR, zosA and mrgA.
Role Repressor
Protein family FUR
Structure (PDB ID) 2FE3

Reference

Pubmed ID 17962296

Experimental evidences

PDB