ENTRAF

An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.

Transcription factor information

General information

ENTRAF ID ENTRAF0025
Gene name embR
Uniprot ID EMBR_MYCTU
Organism Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Aminoacid sequence MAGSATVEKRLDFGLLGPLQMTIDGTPVPSGTPKQRAVLAMLVINRNRPVGVDALITALWEEWPPSGARASIHSYVSNLRKLLGGAGIDPRVVLAAAPPGYRLSIPDNTCDLGRFVAEKTAGVHAAAAGRFEQASRHLSAALREWRGPVLDDLRDFQFVEPFATALVEDKVLAHTAKAEAEIACGRASAVIAELEALTFEHPYREPLWTQLITAYYLSDRQSDALGAYRRVKTTLADDLGIDPGPTLRALNERILRQQPLDAKKSAKTTAAGTVTVLDQRTMASGQQAVAYLHDIASGRGYPLQAAATRIGRLHDNDIVLDSANVSRHHAVIVDTGTNYVINDLRSSNGVHVQHERIRSAVTLNDGDHIRICDHEFTFQISAGTHGGT
FASTA file Download
Length 388

Functional information

Function Uniprot Positively regulates the transcription of the embCAB operon. Exhibits ATPase and GTPase activities.
Role Activator
Protein family Trans_reg_C
Structure (PDB ID) 2FEZ

References

Pubmed ID 1 16585755
Pubmed ID 2 18985025
Pubmed ID 3 21818301

Experimental evidences

AS, qRTPCR