ENTRAF

An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.

Transcription factor information

General information

ENTRAF ID ENTRAF0031
Gene name cmtR
Uniprot ID CMTR_MYCTU
Organism Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Aminoacid sequence MLTCEMRESALARLGRALADPTRCRILVALLDGVCYPGQLAAHLGLTRSNVSNHLSCLRGCGLVVATYEGRQVRYALADSHLARALGELVQVVLAVDTDQPCVAERAASGEAVEMTGS
FASTA file Download
Length 118

Functional information

Function Uniprot Metal-responsive transcriptional repressor for the cmt operon. Binding of cadmium or lead causes the repressor to dissociate from the DNA.
Role Repressor
Protein family ArsR
Structure (PDB ID) 2JSC

References

Pubmed ID 1 12939264
Pubmed ID 2 18985025
Pubmed ID 3 25581030
Pubmed ID 4 21818301

Experimental evidences

AS, CHS