ENTRAF

An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.

Transcription factor information

General information

ENTRAF ID ENTRAF0035
Gene name zur
Uniprot ID ZUR_MYCTU
Organism Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Aminoacid sequence MSAAGVRSTRQRAAISTLLETLDDFRSAQELHDELRRRGENIGLTTVYRTLQSMASSGLVDTLHTDTGESVYRRCSEHHHHHLVCRSCGSTIEVGDHEVEAWAAEVATKHGFSDVSHTIEIFGTCSDCRS
FASTA file Download
Length 130

Functional information

Function Uniprot Global transcriptional regulator involved in zinc homeostasis. Represses the transcription of at least 32 genes, including genes involved in zinc homeostasis, by binding to promoter sequences that contain a conserved 26 bp palindrome, in the presence of zinc.
Role Repressor
Protein family FUR
Structure (PDB ID) 2O03

References

Pubmed ID 1 18985025
Pubmed ID 2 17098899
Pubmed ID 3 25581030

Experimental evidences

AS, MIC, qRTPCR, CHS