ENTRAF

An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.

Transcription factor information

General information

ENTRAF ID ENTRAF0160
Gene name Rv2034
Uniprot ID HTHAR_MYCTU
Organism Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Aminoacid sequence MSTYRSPDRAWQALADGTRRAIVERLAHGPLAVGELARDLPVSRPAVSQHLKVLKTARLVCDRPAGTRRVYQLDPTGLAALRTDLDRFWTRALTGYAQLIDSEGDDT
FASTA file Download
Length 107

Functional information

Function Uniprot Involved in the regulation of lipid metabolism and hypoxic response. Positively regulates transcription of various genes, such as phoP, groEL2 and dosR. Negatively regulates its own transcription. Acts by binding to a specific palindromic sequence motif in promoter regions.
Role Activator; Repressor
Protein family ArsR
Structure (PDB ID) -

References

Pubmed ID 1 19228590
Pubmed ID 2 25581030
Pubmed ID 3 21818301

Experimental evidences

OHRS, CHS