ENTRAF

An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.

Transcription factor information

General information

ENTRAF ID ENTRAF0212
Gene name Rv1353c
Uniprot ID Y1353_MYCTU
Organism Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Aminoacid sequence MQTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAVRRPTATADAPTPGARAKAVAR
FASTA file Download
Length 261

Functional information

Function Uniprot Negatively regulates the expression of the efflux pump Rv0191 upon chloramphenicol exposure. Acts by binding to the Rv0191 promoter region.
Role Repressor
Protein family TetR/AcrR
Structure (PDB ID) -

References

Pubmed ID 1 25581030
Pubmed ID 2 31054279

Experimental evidences

CHS