ENTRAF

An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.

Transcription factor information

General information

ENTRAF ID ENTRAF0225
Gene name smtB
Uniprot ID SMTB_MYCTU
Organism Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Aminoacid sequence MVTSPSTPTAAHEDVGADEVGGHQHPADRFAECPTFPAPPPREILDAAGELLRALAAPVRIAIVLQLRESQRCVHELVDALHVPQPLVSQHLKILKAAGVVTGERSGREVLYRLADHHLAHIVLDAVAHAGEDAI
FASTA file Download
Length 135

Functional information

Function Uniprot Transcriptional regulator involved in zinc homeostasis. Represses the expression of the smtB-zur operon in the absence of zinc. Could act as the metal sensor that controls the expression of zur in response to zinc availability.
Role Repressor
Protein family ArsR
Structure (PDB ID) -

References

Pubmed ID 1 18985025
Pubmed ID 2 21818301

Experimental evidences

AS