ENTRAF

An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.

Transcription factor information

General information

ENTRAF ID ENTRAF0253
Gene name arpA
Uniprot ID AFRP_STRGR
Organism Streptomyces griseus
Aminoacid sequence MAKQARAVQTWRSIVDAAASVFDDYGYERAAISEILRRAKVTKGALYFHFASKEAIAQAIMDEQTSTVEFEQEGSPLQSLVDGGQQFAFALRHNSMARAGTRLSIEGVFLGGPHPWGDWIDATARMLELGQERGEVFPQIDPMVSAKIIVASFTGIQLVSEADSGRADLRGQVAEMWRHILPSIAHPGVIAHIKPEGRVDLAAQAREKAEREEQEARIAAEAKGAGSDAATDSGSRSGGSGLRGGGSGRGPRAGGAGDEGDEEPAGAGVAAGGVVA
FASTA file Download
Length 276

Functional information

Function Uniprot Represses adpA expression by binding to the promoter region in the absence of A-factor, causing repression of streptomycin production and of sporulation.
Role Repressor
Protein family TetR/AcrR
Structure (PDB ID) -

References

Pubmed ID 1 7592371
Pubmed ID 2 9813285
Pubmed ID 3 2502536
Pubmed ID 4 2111804
Pubmed ID 5 9220006
Pubmed ID 6 10540289
Pubmed ID 7 9098075

Experimental evidences

SM