ENTRAF

An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.

Transcription factor information

General information

ENTRAF ID ENTRAF0279
Gene name basR
Uniprot ID BASR_ECOLI
Organism Escherichia coli (strain K12)
Aminoacid sequence MKILIVEDDTLLLQGLILAAQTEGYACDSVTTARMAEQSLEAGHYSLVVLDLGLPDEDGLHFLARIRQKKYTLPVLILTARDTLTDKIAGLDVGADDYLVKPFALEELHARIRALLRRHNNQGESELIVGNLTLNMGRRQVWMGGEELILTPKEYALLSRLMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKARIRTVRGFGYMLVANEEN
FASTA file Download
Length 222

Functional information

Function Uniprot Member of the two-component regulatory system BasS/BasR. BasR induces the transcription of the ugd, ais, arnBCADTEF and eptA-basRS loci, all involved in resistance to polymyxin (By similarity).
Role Activator; Repressor
Protein family Trans_reg_C
Structure (PDB ID) -

References

Pubmed ID 1 8282725
Pubmed ID 2 15569938
Pubmed ID 3 7610040
Pubmed ID 4 9278503
Pubmed ID 5 16738553
Pubmed ID 6 15522865
Pubmed ID 7 22442305

Experimental evidences

BPP, SM, GEA