ENTRAF

An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.

Transcription factor information

General information

ENTRAF ID ENTRAF0317
Gene name comK
Uniprot ID COMK_BACSU
Organism Bacillus subtilis (strain 168)
Aminoacid sequence MSQKTDAPLESYEVNGATIAVLPEEIDGKICSKIIEKDCVFYVNMKPLQIVDRSCRFFGSSYAGRKAGTYEVTKISHKPPIMVDPSNQIFLFPTLSSTRPQCGWISHVHVKEFKATEFDDTEVTFSNGKTMELPISYNSFENQVYRTAWLRTKFQDRIDHRVPKRQEFMLYPKEERTKMIYDFILRELGERY
FASTA file Download
Length 192

Functional information

Function Uniprot A master regulator required for the expression of late competence genes including comC, comE, comG and the bdbDC operon. Receives signals from SrfA, and possibly other regulatory COM genes, and transduces these signals to the late COM genes. Represses transcription of rok. May repress expression of a few genes.
Role Activator; Repressor
Protein family ComK
Structure (PDB ID) -

References

Pubmed ID 1 8196543
Pubmed ID 2 9579061
Pubmed ID 3 9384377
Pubmed ID 4 7783616
Pubmed ID 5 11744713
Pubmed ID 6 11918817
Pubmed ID 7 11948146
Pubmed ID 8 11849533

Experimental evidences

BPP