An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.
| ENTRAF ID | ENTRAF0321 |
| Gene name | copR |
| Uniprot ID | COPR_PSEUB |
| Organism | Pseudomonas syringae pv. tomato |
| Aminoacid sequence | MKLLVAEDEPKTGIYLQQGLREAGFNVDRVVTGTDAVDQALNEAYDLLILDVMMPGLDGWEVIRRLRTAGQPVPVLFLTARDGVDDRVKGLELGADDYLVKPFALSELLARVRTLLRRGSSLQVQTSLQIGDLQVDLLKRRATRGGKRIELTAKEFALLELLMRRQGEVLSKSLIASQVWDMNFDSDTNVIEVAIRRLRAKIDDDFEVKLLHTCRGMGYMLEAQDEG |
| FASTA file | Download |
| Length | 227 |
| Function Uniprot | Member of the two-component regulatory system CopS/CopR. Involved in the activation of copper resistance gene operon CopABCD. Phosphorylation of CopR by CopS would convert it into an active state to induce expression of the cop operon by binding to a specific site on the cop operon promoter (cop box) and possibly by facilitating the binding of RNA polymerase to the cop promoter. CopR also binds to the chromosomally encoded cop operon promoter. May also be involved in basic copper metabolism. |
| Role | Activator |
| Protein family | Trans_reg_C |
| Structure (PDB ID) | - |