An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.
| ENTRAF ID | ENTRAF0322 |
| Gene name | copY |
| Uniprot ID | COPY_ENTHA |
| Organism | Enterococcus hirae (strain ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258) |
| Aminoacid sequence | MEEKRVLIKISDSEWEVMRVIWTLGQANAQQITQILADSMDWKVATVKTLLGRLVKKEALWTEQEGKKFIYHPAVSEMENVRSATENLFSHICAKRVGATIADLVEEATLTQEDIQQIMKQLNKKEPVETIECNCIPGQCECKKQ |
| FASTA file | Download |
| Length | 145 |
| Function Uniprot | Acts as a copper responsive repressor. Binds to DNA in complex with Zn(2+), repressing the transcription of the copYZAB operon. Exchange of the bound zinc by two copper ions delivered by CopZ Cu(1+)-bound form causes release of CopY from the promoter, leading to the transcription of the operon. |
| Role | Repressor |
| Protein family | Penicillinase_R |
| Structure (PDB ID) | - |