An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.
ENTRAF ID | ENTRAF0331 |
Gene name | cspD |
Uniprot ID | CSPD_ECOLI |
Organism | Escherichia coli (strain K12) |
Aminoacid sequence | MEKGTVKWFNNAKGFGFICPEGGGEDIFAHYSTIQMDGYRTLKAGQSVQFDVHQGPKGNHASVIVPVEVEAAVA |
FASTA file | Download |
Length | 74 |
Function Uniprot | Inhibits DNA replication at both initiation and elongation steps, most probably by binding to the opened, single-stranded regions at replication forks. Plays a regulatory role in chromosomal replication in nutrient-depleted cells.; Involved in persister cell formation, acting downstream of mRNA interferase (toxin) MqsR. Overproduction is toxic. |
Role | Repressor |
Protein family | CSD |
Structure (PDB ID) | - |