ENTRAF

An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.

Transcription factor information

General information

ENTRAF ID ENTRAF0334
Gene name ctrA
Uniprot ID CTRA_BRUAB
Organism Brucella abortus biovar 1 (strain 9-941)
Aminoacid sequence MRVLLIEDDSAIAQSIELMLKSESFNVYTTDLGEEGIDLGKLYDYDIILLDLNLPDMSGYEVLRTLRLSKVKTPILILSGMAGIEDKVRGLGFGADDYMTKPFHKDELIARIHAIVRRSKGHAQSVITTGDLVVNLDAKTVEVAGQRVHLTGKEYQMLELLSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLDAVSGNQSYIETVWGRGYVLREPDAEMRESA
FASTA file Download
Length 232

Functional information

Function Uniprot Component of a regulatory phosphorelay system that controls B.abortus cell growth, division, and intracellular survival inside mammalian host cells. This signaling pathway is composed of CckA, ChpT, CtrA and CpdR. CtrA is a response regulator substrate of ChpT (By similarity). When phosphorylated, directly regulates the expression of ccrM. Is also probably involved in the transcriptional regulation of rpoD, pleC, minC and ftsE genes.
Role Unknown
Protein family Trans_reg_C
Structure (PDB ID) -

References

Pubmed ID 1 11929544
Pubmed ID 2 15805518

Experimental evidences

BPP, BCE, SM