ENTRAF

An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.

Transcription factor information

General information

ENTRAF ID ENTRAF0340
Gene name cysB
Uniprot ID CYSB_SALTY
Organism Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Aminoacid sequence MKLQQLRYIVEVVNHNLNVSSTAEGLYTSQPGISKQVRMLEDELGIQIFARSGKHLTQVTPAGQEIIRIAREVLSKVDAIKSVAGEHTWPDKGSLYIATTHTQARYALPGVIKGFIERYPRVSLHMHQGSPTQIAEAVSKGNADFAIATEALHLYDDLVMLPCYHWNRSIVVTPDHPLAATSSVTIEALAQYPLVTYTFGFTGRSELDTAFNRAGLTPRIVFTATDADVIKTYVRLGLGVGVIASMAVDPLADPDLVRIDAHDIFSHSTTKIGFRRSTFLRSYMYDFIQRFAPHLTRDVVDTAVALRSNEEIEAMFQDIKLPEK
FASTA file Download
Length 324

Functional information

Function Uniprot This protein is a positive regulator of gene expression for the cysteine regulon, a system of 10 or more loci involved in the biosynthesis of L-cysteine from inorganic sulfate. The inducer for CysB is N-acetylserine. CysB inhibits its own transcription.
Role Activator; Repressor
Protein family LysR
Structure (PDB ID) 4GWO

References

Pubmed ID 1 3032952
Pubmed ID 2 11677609
Pubmed ID 3 3032953
Pubmed ID 4 1435253
Pubmed ID 5 2254265
Pubmed ID 6 2105304

Experimental evidences

BPP