An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.
ENTRAF ID | ENTRAF0394 |
Gene name | relJ |
Uniprot ID | RELJ_MYCTU |
Organism | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
Aminoacid sequence | MSISASEARQRLFPLIEQVNTDHQPVRITSRAGDAVLMSADDYDAWQETVYLLRSPENARRLMEAVARDKAGHSAFTKSVDELREMAGGEE |
FASTA file | Download |
Length | 91 |
Function Uniprot | Antitoxin component of a toxin-antitoxin (TA) module. A probable antitoxin for the putative mRNA interferase RelK. Upon expression in E.coli but not in M.smegmatis this protein neutralizes E.coli YoeB.; Binds to and represses its own promoter, in combination with RelK repression is somewhat lessened. Several DNA-protein complexes are formed in vitro depending on the RelJ:RelK ratio. |
Role | Repressor |
Protein family | PhdYeFM_antitox |
Structure (PDB ID) | 3CTO |