ENTRAF

An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.

Transcription factor information

General information

ENTRAF ID ENTRAF0411
Gene name rot
Uniprot ID ROT_STAAC
Organism Staphylococcus aureus (strain COL)
Aminoacid sequence MHKLAHTSFGIVGMFVNTCIVAKYVIINWEMFSMKKVNNDTVFGILQLETLLGDINSIFSEIESEYKMSREEILILLTLWQKGFMTLKEMDRFVEVKPYKRTRTYNNLVELEWIYKERPVDDERTVIIHFNEKLQQEKVELLNFISDAIASRATAMQNSLNAIIAV
FASTA file Download
Length 166

Functional information

Function Uniprot Global regulator with both positive and negative effects that mediates modulation of several genes involved in virulence. Also, modulates the expression of genes not previously implicated in pathogenesis (By similarity).
Role Activator; Repressor
Protein family MarR
Structure (PDB ID) -

References

Pubmed ID 1 12511508
Pubmed ID 2 15774886
Pubmed ID 3 17384184

Experimental evidences

BPP, CHS