ENTRAF

An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.

Transcription factor information

General information

ENTRAF ID ENTRAF0412
Gene name rot
Uniprot ID ROT_STAAM
Organism Staphylococcus aureus (strain Mu50 / ATCC 700699)
Aminoacid sequence MHKLAHTSFGIVGMFVNTCMVAKYVIINWEMFSMKKVNNDTVFGILQLETLLGDINSIFSEIESEYKMSREEILILLTLWQKGSMTLKEMDRFVEVKPYKRTRTYNNLVELEWIYKERPVDDERTVIIHFNEKLQQEKVELLNFISDAIASRATAMQNSLNAIIAV
FASTA file Download
Length 166

Functional information

Function Uniprot Global regulator with both positive and negative effects that mediates modulation of several genes involved in virulence. Also, modulates the expression of genes not previously implicated in pathogenesis (By similarity).
Role Activator; Repressor
Protein family MarR
Structure (PDB ID) -

References

Pubmed ID 1 22685286
Pubmed ID 2 11418146

Experimental evidences

BPP