ENTRAF

An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.

Transcription factor information

General information

ENTRAF ID ENTRAF0417
Gene name saeR
Uniprot ID SAER_STAAC
Organism Staphylococcus aureus (strain COL)
Aminoacid sequence MTHLLIVDDEQDIVDICQTYFEYEGYKVTTTTSGKEAISLLSNDIDIMVLDIMMPEVNGYDIVKEMKRQKLDIPFIYLTAKTQEHDTIYALTLGADDYVKKPFSPRELVLRINNLLTRMKKYHHQPVEQLSFDELTLINLSKVVTVNGHEVPMRIKEFELLWYLASRENEVISKSELLEKVWGYDYYEDANTVNVHIHRIREKLEKESFTTYTITTVWGLGYKFERSR
FASTA file Download
Length 228

Functional information

Function Uniprot Member of the two-component regulatory system SaeR/SaeS involved in the regulation of staphylococcal virulence factors in a strain-dependent fashion. Probably functions as a transcriptional regulator via a specific DNA-binding domain, recognizing motifs near the promoter sequences of target genes (By similarity). Modulates the expression of several genes.
Role Unknown
Protein family Trans_reg_C
Structure (PDB ID) -

References

Pubmed ID 1 17079681
Pubmed ID 2 15774886
Pubmed ID 3 17079681

Experimental evidences

MIC