ENTRAF

An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.

Transcription factor information

General information

ENTRAF ID ENTRAF0438
Gene name sarV
Uniprot ID SARV_STAA8
Organism Staphylococcus aureus (strain NCTC 8325)
Aminoacid sequence MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
FASTA file Download
Length 116

Functional information

Function Uniprot Part of the pathway by which MgrA and SarA control autolysis. Involved in regulation of virulence and autolysis genes such as hla, splA, aur, scp, lrgB, scdA and atl. May also act as an activator for the expression of regulatory genes agr, lytSR and ArlRS.
Role Activator
Protein family MarR
Structure (PDB ID) -

References

Pubmed ID 1 15292128
Pubmed ID 2 15292128

Experimental evidences

BCE, GEA