ENTRAF

An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.

Transcription factor information

General information

ENTRAF ID ENTRAF0440
Gene name sarX
Uniprot ID SARX_STAA8
Organism Staphylococcus aureus (strain NCTC 8325)
Aminoacid sequence MNTEKLETLLGFYKQYKALSEYIDKKYKLSLNDLAVLDLTMKHCKDEKVLMQSFLKTAMDELDLSRTKLLVSIRRLIEKERLSKVRSSKDERKIYIYLNNDDISKFNALFEDVEQFLNI
FASTA file Download
Length 119

Functional information

Function Uniprot Involved in the regulation of virulence genes. Acts as a repressor of the agr locus and consequently targets genes regulated by the agr system such as sspA, hla and hlb. Binds directly to the agr promoter region.
Role Repressor
Protein family MarR
Structure (PDB ID) 5HS5

References

Pubmed ID 1 16740935
Pubmed ID 2 16740935

Experimental evidences

GEA