An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.
| ENTRAF ID | ENTRAF0446 |
| Gene name | tcmR |
| Uniprot ID | TCMR_STRGA |
| Organism | Streptomyces glaucescens |
| Aminoacid sequence | MDSAETDTPSTRSTPNGPGLRQRKLRRTRDQLIREALELFLAQGYEHTTVEQIAEAVEVHPRTFFRHFASKEEVALTPISAIDEAFLAALEVRPAGENPLQAMSGAFRAVLGRVRDGELEGVDGALHMAMMRLVERTPGLLAEYLRRSEEMEGRLARIIAAREGVDLDDDFRPRFIVAVFKAVGRVVSREWYLRADTDLEALSVAFESALDSLRPELFADWRRPGA |
| FASTA file | Download |
| Length | 226 |
| Function Uniprot | Represses transcription of the divergently oriented tcmR and tcmA (tetracenomycin C resistance and export) genes by binding to an intergenic operator region. This binding is inhibited by tetracenomycin C. |
| Role | Repressor |
| Protein family | TetR/AcrR |
| Structure (PDB ID) | - |