ENTRAF

An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.

Transcription factor information

General information

ENTRAF ID ENTRAF0469
Gene name araC
Uniprot ID ARAC_ECOLI
Organism Escherichia coli (strain K12)
Aminoacid sequence MAEAQNDPLLPGYSFNAHLVAGLTPIEANGYLDFFIDRPLGMKGYILNLTIRGQGVVKNQGREFVCRPGDILLFPPGEIHHYGRHPEAREWYHQWVYFRPRAYWHEWLNWPSIFANTGFFRPDEAHQPHFSDLFGQIINAGQGEGRYSELLAINLLEQLLLRRMEAINESLHPPMDNRVREACQYISDHLADSNFDIASVAQHVCLSPSRLSHLFRQQLGISVLSWREDQRISQAKLLLSTTRMPIATVGRNVGFDDQLYFSRVFKKCTGASPSEFRAGCEEKVNDVAVKLS
FASTA file Download
Length 292

Functional information

Function Uniprot This protein controls the expression of at least six genes that are involved in the transport and catabolism of L-arabinose. It regulates initiation of transcription of the araBAD operon and it also controls its own synthesis. The L-arabinose operon displays both positive and negative regulation through AraC.
Role Activator; Repressor
Protein family AraC/XylS
Structure (PDB ID) 1XJA

References

Pubmed ID 1 7019009
Pubmed ID 2 7008027
Pubmed ID 3 6283093
Pubmed ID 4 1630901
Pubmed ID 5 9278503
Pubmed ID 6 16738553
Pubmed ID 7 6160371
Pubmed ID 8 9298644
Pubmed ID 9 9367758
Pubmed ID 10 9103202
Pubmed ID 11 22383259
Pubmed ID 12 9696773

Experimental evidences

BPP, SM, GEA