An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.
| ENTRAF ID | ENTRAF0471 |
| Gene name | argR |
| Uniprot ID | ARGR_ECOLI |
| Organism | Escherichia coli (strain K12) |
| Aminoacid sequence | MRSSAKQEELVKAFKALLKEEKFSSQGEIVAALQEQGFDNINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTSSPLKNLVLDIDYNDAVVVIHTSPGAAQLIARLLDSLGKAEGILGTIAGDDTIFTTPANGFTVKDLYEAILELFDQEL |
| FASTA file | Download |
| Length | 156 |
| Function Uniprot | Negatively controls the expression of the four operons of arginine biosynthesis in addition to the carAB operon. Predominantly interacts with A/T residues in ARG boxes. It also binds to a specific site in cer locus. Thus it is essential for cer-mediated site-specific recombination in ColE1. It is necessary for monomerization of the plasmid ColE1. |
| Role | Activator; Repressor |
| Protein family | ArgR |
| Structure (PDB ID) | 1AOY |