An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.
ENTRAF ID | ENTRAF0490 |
Gene name | csgD |
Uniprot ID | CSGD_ECOLI |
Organism | Escherichia coli (strain K12) |
Aminoacid sequence | MFNEVHSIHGHTLLLITKSSLQATALLQHLKQSLAITGKLHNIQRSLDDISSGSIILLDMMEADKKLIHYWQDTLSRKNNNIKILLLNTPEDYPYRDIENWPHINGVFYSMEDQERVVNGLQGVLRGECYFTQKLASYLITHSGNYRYNSTESALLTHREKEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR |
FASTA file | Download |
Length | 216 |
Function Uniprot | The master regulator for adhesive curli fimbriae expression; necessary for transcription of the csgBAC/ymdA operon. Plays a positive role in biofilm formation. May have the capability to respond to starvation and/or high cell density by activating csgBA transcription. Low-level constitutive expression confers an adherent curli fimbriae-expressing phenotype, up-regulates 10 genes and down-regulates 14 others. |
Role | Activator; Repressor |
Protein family | GerE |
Structure (PDB ID) | - |