An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.
| ENTRAF ID | ENTRAF0505 |
| Gene name | dpiA |
| Uniprot ID | DPIA_ECOLI |
| Organism | Escherichia coli (strain K12) |
| Aminoacid sequence | MTAPLTLLIVEDETPLAEMHAEYIRHIPGFSQILLAGNLAQARMMIERFKPGLILLDNYLPDGRGINLLHELVQAHYPGDVVFTTAASDMETVSEAVRCGVFDYLIKPIAYERLGQTLTRFRQRKHMLESIDSASQKQIDEMFNAYARGEPKDELPTGIDPLTLNAVRKLFKEPGVQHTAETVAQALTISRTTARRYLEYCASRHLIIAEIVHGKVGRPQRIYHSG |
| FASTA file | Download |
| Length | 226 |
| Function Uniprot | Member of the two-component regulatory system DpiA/DpiB, which is essential for expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. Could be involved in response to both the presence of citrate and external redox conditions. Regulates the transcription of citCDEFXGT, dpiAB, mdh and exuT. Binds specifically to the dpiB-citC intergenic region. |
| Role | Activator; Repressor |
| Protein family | Crp |
| Structure (PDB ID) | - |