An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.
| ENTRAF ID | ENTRAF0520 |
| Gene name | fur |
| Uniprot ID | FUR_ECOLI |
| Organism | Escherichia coli (strain K12) |
| Aminoacid sequence | MTDNNTALKKAGLKVTLPRLKILEVLQEPDNHHVSAEDLYKRLIDMGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEFSDDSIEARQREIAAKHGIRLTNHSLYLYGHCAEGDCREDEHAHEGK |
| FASTA file | Download |
| Length | 148 |
| Function Uniprot | Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulates the expression of several outer-membrane proteins including the iron transport operon. |
| Role | Activator; Repressor |
| Protein family | FUR |
| Structure (PDB ID) | 2FU4 |