ENTRAF

An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.

Transcription factor information

General information

ENTRAF ID ENTRAF0521
Gene name gadE
Uniprot ID GADE_ECOLI
Organism Escherichia coli (strain K12)
Aminoacid sequence MIFLMTKDSFLLQGFWQLKDNHEMIKINSLSEIKKVGNKPFKVIIDTYHNHILDEEAIKFLEKLDAERIIVLAPYHISKLKAKAPIYFVSRKESIKNLLEITYGKHLPHKNSQLCFSHNQFKIMQLILKNKNESNITSTLNISQQTLKIQKFNIMYKLKLRRMSDIVTLGITSYF
FASTA file Download
Length 175

Functional information

Function Uniprot Regulates the expression of several genes involved in acid resistance. Required for the expression of gadA and gadBC, among others, regardless of media or growth conditions. Binds directly to the 20 bp GAD box found in the control regions of both loci.
Role Activator; Repressor
Protein family GerE
Structure (PDB ID) -

Reference

Pubmed ID 26527724

Experimental evidences

BPP, GEA