An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.
| ENTRAF ID | ENTRAF0551 |
| Gene name | lrp |
| Uniprot ID | LRP_ECOLI |
| Organism | Escherichia coli (strain K12) |
| Aminoacid sequence | MVDSKKRPGKDLDRIDRNILNELQKDGRISNVELSKRVGLSPTPCLERVRRLERQGFIQGYTALLNPHYLDASLLVFVEITLNRGAPDVFEQFNTAVQKLEEIQECHLVSGDFDYLLKTRVPDMSAYRKLLGETLLRLPGVNDTRTYVVMEEVKQSNRLVIKTR |
| FASTA file | Download |
| Length | 164 |
| Function Uniprot | Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes. |
| Role | Activator; Repressor |
| Protein family | AsnC |
| Structure (PDB ID) | 2GQQ |