ENTRAF

An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.

Transcription factor information

General information

ENTRAF ID ENTRAF0559
Gene name mcbR
Uniprot ID MCBR_ECOLI
Organism Escherichia coli (strain K12)
Aminoacid sequence MPGTGKMKHVSLTLQVENDLKHQLSIGALKPGARLITKNLAEQLGMSITPVREALLRLVSVNALSVAPAQAFTVPEVGKRQLDEINRIRYELELMAVALAVENLTPQDLAELQELLEKLQQAQEKGDMEQIINVNRLFRLAIYHRSNMPILCEMIEQLWVRMGPGLHYLYEAINPAELREHIENYHLLLAALKAKDKEGCRHCLAEIMQQNIAILYQQYNR
FASTA file Download
Length 221

Functional information

Function Uniprot Important for biofilm formation. Represses expression of McbA by binding to its promoter region, which prevents colanic acid overproduction and mucoidy.
Role Activator; Repressor
Protein family GntR
Structure (PDB ID) -

Reference

Pubmed ID 26527724

Experimental evidences

BPP, GEA