ENTRAF

An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.

Transcription factor information

General information

ENTRAF ID ENTRAF0561
Gene name metJ
Uniprot ID METJ_ECOLI
Organism Escherichia coli (strain K12)
Aminoacid sequence MAEWSGEYISPYAEHGKKSEQVKKITVSIPLKVLKILTDERTRRQVNNLRHATNSELLCEAFLHAFTGQPLPDDADLRKERSDEIPEAAKEIMREMGINPETWEY
FASTA file Download
Length 105

Functional information

Function Uniprot This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. It is also autoregulated.
Role Repressor
Protein family MetJ
Structure (PDB ID) 1CMA

Reference

Pubmed ID 26527724

Experimental evidences

BPP, SM, GEA