An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.
| ENTRAF ID | ENTRAF0572 |
| Gene name | mtlR |
| Uniprot ID | MTLR_ECOLI |
| Organism | Escherichia coli (strain K12) |
| Aminoacid sequence | MVDQAQDTLRPNNRLSDMQATMEQTQAFENRVLERLNAGKTVRSFLITAVELLTEAVNLLVLQVFRKDDYAVKYAVEPLLDGDGPLGDLSVRLKLIYGLGVINRQEYEDAELLMALREELNHDGNEYAFTDDEILGPFGELHCVAALPPPPQFEPADSSLYAMQIQRYQQAVRSTMVLSLTELISKISLKKAFQK |
| FASTA file | Download |
| Length | 195 |
| Function Uniprot | Involved in the repression of the expression of the mannitol mtlADR operon. Does not bind the operator/promoter regulatory region of this operon. Therefore, seems to belong to a new class of transcription factors in bacteria that may regulate gene expression indirectly, perhaps as a part of a larger transcriptional complex. |
| Role | Repressor |
| Protein family | MtlR |
| Structure (PDB ID) | - |