An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.
| ENTRAF ID | ENTRAF0577 |
| Gene name | nanR |
| Uniprot ID | NANR_ECOLI |
| Organism | Escherichia coli (strain K12) |
| Aminoacid sequence | MGLMNAFDSQTEDSSPAIGRNLRSRPLARKKLSEMVEEELEQMIRRREFGEGEQLPSERELMAFFNVGRPSVREALAALKRKGLVQINNGERARVSRPSADTIIGELSGMAKDFLSHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIDLLAKALEINSQSLDNNAAFIRSDVDFHRVLAEIPGNPIFMAIHVALLDWLIAARPTVTDQALHEHNNVSYQQHIAIVDAIRRHDPDEADRALQSHLNSVSATWHAFGQTTNKKK |
| FASTA file | Download |
| Length | 263 |
| Function Uniprot | Transcriptional repressor that controls expression of the genes required for the catabolism of sialic acids. Represses expression of the nanATEK-yhcH, nanCMS and yjhBC operons. Acts by binding directly to the Nan box, a region of approximately 30 bp covering the promoter region. |
| Role | Activator; Repressor |
| Protein family | GntR |
| Structure (PDB ID) | - |