ENTRAF

An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.

Transcription factor information

General information

ENTRAF ID ENTRAF0606
Gene name rob
Uniprot ID ROB_ECOLI
Organism Escherichia coli (strain K12)
Aminoacid sequence MDQAGIIRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKSAVALRLTARPILDIALQYRFDSQQTFTRAFKKQFAQTPALYRRSPEWSAFGIRPPLRLGEFTMPEHKFVTLEDTPLIGVTQSYSCSLEQISDFRHEMRYQFWHDFLGNAPTIPPVLYGLNETRPSQDKDDEQEVFYTTALAQDQADGYVLTGHPVMLQGGEYVMFTYEGLGTGVQEFILTVYGTCMPMLNLTRRKGQDIERYYPAEDAKAGDRPINLRCELLIPIRR
FASTA file Download
Length 289

Functional information

Function Uniprot Binds to the right arm of the replication origin oriC of the chromosome. Rob binding may influence the formation of the nucleoprotein structure, required for oriC function in the initiation of replication.
Role Activator; Repressor
Protein family AraC/XylS
Structure (PDB ID) 1D5Y

References

Pubmed ID 1 8449900
Pubmed ID 2 8449900
Pubmed ID 3 7610040
Pubmed ID 4 9278503
Pubmed ID 5 16738553

Experimental evidences

BPP, SM, GEA, IEP