An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.
ENTRAF ID | ENTRAF0623 |
Gene name | trpR |
Uniprot ID | TRPR_ECOLI |
Organism | Escherichia coli (strain K12) |
Aminoacid sequence | MAQQSPYSAAMAEQRHQEWLRFVDLLKNAYQNDLHLPLLNLMLTPDEREALGTRVRIVEELLRGEMSQRELKNELGAGIATITRGSNSLKAAPVELRQWLEEVLLKSD |
FASTA file | Download |
Length | 108 |
Function Uniprot | This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. |
Role | Repressor |
Protein family | TrpR |
Structure (PDB ID) | 1CO0 |