An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.
| ENTRAF ID | ENTRAF0633 |
| Gene name | yefM |
| Uniprot ID | YEFM_ECOLI |
| Organism | Escherichia coli (strain K12) |
| Aminoacid sequence | MRTISYSEARQNLSATMMKAVEDHAPILITRQNGEACVLMSLEEYNSLEETAYLLRSPANARRLMDSIDSLKSGKGTEKDIIE |
| FASTA file | Download |
| Length | 83 |
| Function Uniprot | Antitoxin component of a type II toxin-antitoxin (TA) module. Antitoxin that counteracts the effect of the YoeB toxin. YefM binds to the promoter region of the yefM-yeoB operon to repress transcription, YeoB acts as a corepressor. |
| Role | Activator; Repressor |
| Protein family | PhdYeFM_antitox |
| Structure (PDB ID) | 2A6Q |