ENTRAF

An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.

Transcription factor information

General information

ENTRAF ID ENTRAF0642
Gene name ypdB
Uniprot ID YPDB_ECOLI
Organism Escherichia coli (strain K12)
Aminoacid sequence MKVIIVEDEFLAQQELSWLIKEHSQMEIVGTFDDGLDVLKFLQHNRVDAIFLDINIPSLDGVLLAQNISQFAHKPFIVFITAWKEHAVEAFELEAFDYILKPYQESRITGMLQKLEAAWQQQQTSSTPAATVTRENDTINLVKDERIIVTPINDIYYAEAHEKMTFVYTRRESYVMPMNITEFCSKLPPSHFFRCHRSFCVNLNKIREIEPWFNNTYILRLKDLDFEVPVSRSKVKEFRQLMHL
FASTA file Download
Length 244

Functional information

Function Uniprot Member of the two-component regulatory system YpdA/YpdB, which is part of a nutrient-sensing regulatory network composed of YpdA/YpdB, the high-affinity pyruvate signaling system BtsS/BtsR and their respective target proteins, YhjX and YjiY. YpdB regulates expression of yhjX by binding to its promoter region. Activation of the YpdA/YpdB signaling cascade also promotes BtsS/BtsR-mediated yjiY expression.
Role Activator
Protein family LytTR
Structure (PDB ID) -

Reference

Pubmed ID 26527724

Experimental evidences

BPP, BCE, SM