ENTRAF

An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.

Transcription factor information

General information

ENTRAF ID ENTRAF0657
Gene name mraZ
Uniprot ID MRAZ_ECOLI
Organism Escherichia coli (strain K12)
Aminoacid sequence MFRGATLVNLDSKGRLSVPTRYREQLLENAAGQMVCTIDIYHPCLLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHAGLTKEVMLVGQFNKFELWDETTWHQQVKEDIDAEQLATGDLSERLQDLSL
FASTA file Download
Length 152

Functional information

Function Uniprot Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.
Role Repressor
Protein family MazE_antitoxin
Structure (PDB ID) -

Reference

Pubmed ID 26527724

Experimental evidences

BPP, BCE, SM, GEA