An Encyclopedia of well-annotated DNA-binding TRanscription factors in Bacteria and Archaea.
| ENTRAF ID | ENTRAF0661 |
| Gene name | higA |
| Uniprot ID | HIGA_ECOLI |
| Organism | Escherichia coli (strain K12) |
| Aminoacid sequence | MIAIADILQAGEKLTAVAPFLAGIQNEEQYTQALELVDHLLLNDPENPLLDLVCAKITAWEESAPEFAEFNAMAQAMPGGIAVIRTLMDQYGLTLSDLPEIGSKSMVSRVLSGKRKLTLEHAKKLATRFGISPALFID |
| FASTA file | Download |
| Length | 138 |
| Function Uniprot | Antitoxin component of a type II toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin; overexpression prevents HigB-mediated cessation of cell growth and inhibition of cell proliferation. |
| Role | Repressor |
| Protein family | SinR |
| Structure (PDB ID) | 5IFG |